There is a plant in my kitchen that has been alive longer than I have known what to do with it. I did not start it. It was given to me, in a piece, from a life that came before mine. A hoya bella: long, trailing, generous. When it blooms, it sends out clusters the color of champagne that smell exactly like chocolate. It is one of more than a hundred hoyas I keep now. Some hang from broken tree branches, some line the kitchen window, some live on my bedside table or my desk. Everywhere there is a little light and a ledge or a place to hang from, there is a hoya. They grow in different shapes and at different speeds: some heart-shaped, some so slow you measure their growth in years, some that take a decade before they give you their first flower. I love them for what they carry. They are a part of me because of how they produce, how they give birth to life.
I have been propagating the hoya bella for years. A cutting, a glass of water, a few weeks of patience. Then a root, then a small plant, then a daughter. I have daughters of this plant living all over the country now, in homes I visit and homes I never see. Each one started from the same mother. Each one carries something I cannot fully name. Not a gene exactly, not a memory, but something. The stuff that lives in the tissue of a thing and travels forward whether or not anyone is watching.
A friend of mine has a sourdough mother. Not a recipe. A living starter, fed and tended across years, that carries the essence of every hand that has cared for it. You cannot replicate it from scratch. You can only receive a piece of it from someone who already has it, keep it alive, and pass it forward. The bread it makes is specific. It tastes like continuity. It tastes like something that has survived long enough to become itself.
That is what propagation is. Not copying. Not reproducing. Carrying something living forward into conditions it has never known, and trusting it to root.
I am taking root differently now. My partner plant did not make it. What remains is what he gave me before the end. Not tidy, not resolved, but real in the way that real things are. I am learning what that means the way we learn things that cannot be taught: slowly, in the body, the way a cutting learns water before it learns soil.
The hoya bella is still in my kitchen. It is still going. Whatever it carries, it has been carrying longer than I have been watching. I tend it because it was tended before me. I will pass a piece of it forward when the time is right. That is the only contract. Keep it alive. Give a piece away. Trust that what it carries will find its way into whatever room it grows in next.
Some things survive us by design.
I went to Mexico to rest. That was the whole plan. Rest, decompress, let the pace of La Mision do what it does — slow everything down until you can hear yourself again.
I did not go to find a Mayan hand-loomed table runner. I did not go to find a keeping garment made the way Aztec women made them, or a fire-pitted terracotta bird, or a friend named Carmen, or the beginning of something I am still building. None of that was on the list. The list said: rest.
But I said yes to one small thing. A walk. A conversation at the door. Carmen saying come, I want to show you something. I said yes to that, and the thread had more thread.
This is what I have learned about the things that actually change your life: almost none of them appeared as what they were. They appeared as something small. A lunch. A phone call you almost didn't take. A door you walked through because someone you trusted held it open. You said yes to the small thing, and the small thing had more behind it, and more behind that, and eventually you were somewhere you never could have planned your way to.
Most of us are holding a thread right now that we haven't pulled. It doesn't look like an opportunity yet. It looks like a small yes. It looks like a conversation that might be nothing. It looks like a Sunday morning drive to Rosarito with a woman named Carmen who has lived two doors down for twenty-three years.
Pull it.
The thread has more thread. It always does.
What is the small yes you have been putting off? What thread are you holding right now that you haven't had the courage — or the quiet — to follow?
My father died when I was nineteen. I only knew him into his forties. What I knew about his gut is this: on Sunday mornings, the three of us waited in the car in the driveway — my mother, my sister, and me — while he finished his business inside. We never said anything about it. It was just the way Sunday mornings were. Whether that was a condition or just a man who needed more time, I honestly cannot say. He was gone before I knew enough to ask.
What I do know is this: my mother's intestines are staging their own battles now. My sister was diagnosed with Crohn's disease in her twenties — surgery, treatment, the long management of something that does not fully resolve. The gut thread is real. It runs through the women I came from.
It skipped me. And I have spent a long time quietly turning that over.
Here is what makes it interesting. I am the least medically trained person in my family. My mother was a psychiatric nurse practitioner — she spent decades inside the science of mind and body, and she gave that expertise to her patients the way people who are built to give always do: completely, until there was nothing left at the end of the day for herself. My sister has a master's degree in rehabilitation counseling. She runs a flourishing business helping veterans heal through movement — she knows the body, she understands trauma, she works every day at the intersection of both. Their education makes mine look like a curiosity project.
My degree is in physical science. I was trained to explain how light, waves, sound, and planetary conditions shape the world outside us — and then, eventually, inside us. I came to the body the way a physicist comes to any system: from the outside in. Not from clinical knowledge but from environmental observation. What forces are acting on this? What is moving, what is still, what is absorbing what?
Maybe that is the difference. Not that I knew more. Not that I did better. But that I came at my own body from a completely different angle — and that angle, by accident or design, happened to interrupt a pattern that had been running through my family for generations.
I was the pickiest eater as a child, refusing things I couldn't explain. I have moved every three years since college, never long enough in one place to fully absorb it. I have been running since I was twenty-four. And a few years ago I signed up for the All of Us Research Program — an NIH initiative where you give blood, urine, saliva, hair, nail clippings, all of it — because I wanted to know what my body was made of, and because I wanted to give something useful to science.
What came back: 59 genes tested for serious disease. Nothing significant found. And a pharmacogenomics report showing that my body processes certain things differently than the average person. My internal chemistry has its own relationship with the standard charts.
This is what epigenetics is starting to tell us: the genes we carry are not a sentence. They are a disposition. Three women can carry the same family thread and express it differently — not because one was smarter or more disciplined or more devoted to her health, but because the forces acting on each system were genuinely different.
The gut pattern is real in my family. It just landed differently in each of us.
What forces have been acting on your system? Not just what you inherited — but what, without knowing it, you may have already interrupted.
It was made by an Aztec woman who needed both hands free while keeping her child from the world's edges: warm, close, safe and held while she cooked or sold or worked through the hours a day asks of you when the work will not pause for love. Most people call this an impossible problem. She called it a garment.
The solution was the garment itself. Close-knit linen, hand-knotted pompoms in colors that knew what they were doing. The child went under. The mother's hands went out. The two things that both needed tending got tended at the same time. She created the solution. She threaded them together and kept moving. When the child was put to bed, she untied the garment from her waist, drew it to her shoulders, and tied it safe around her neck. The keeping continued. The garment just changed what it was holding.
This is the Women Who Built entry that has no famous name in it. It belongs to a woman whose name no record kept — an Aztec woman who looked at an impossible problem and solved it with her hands, with linen, with the specific knowledge of someone who could not afford to solve it poorly. Now her invention has changed. Fausto found it. He brought it to a small store in Rosarita, Baja California, where it waited in finely woven linen with hand-knotted pompoms for someone who would understand what she was holding. Holly found the store because she had asked for a friend, and the asking led to Carmen, and Carmen brought her there the way friends bring each other to the places they love. It lives now at the end of a bed in Virginia. The function has transmuted into art. The story gets to keep being told.
We carry things from women we will never know. Their solutions live in our hands before we understand where they came from.
That is the thread that does not break.
In Issue 7, I told you I ordered something that was going to change the way I think about age. In Issue 8, I told you it was the kind of thing that makes you check the mail twice.
It is still on its way. The kit is in the mail. When those results land, you will be the first to know what my biological age actually says — because that reveal deserves the full story, not a rushed one.
But while I was waiting, another set of results came back. One I have been sitting on for a while now, wondering when the right moment was to share it.
A few years ago I signed up for the All of Us Research Program. It is an NIH initiative — one of the largest research efforts of its kind — that collects biological samples from hundreds of thousands of volunteers to study the full range of factors that shape human health. The process was not simple. There were forms to sign. A visit to a medical center. Blood. Urine. Saliva. Hair. Nail clippings. All of it offered willingly, because I wanted to know what I was made of, and because I wanted the data to be useful to someone beyond just me.
Here is what came back.
A team of scientists at the Broad Institute of MIT and Harvard examined 59 of my genes — the ones most commonly linked to serious hereditary disease. Cancer genes. Cardiac genes. Rare syndromes. The full list of things that can run quietly through a family until they don't.
In every single one: nothing significant found.
That is not nothing. That is 59 threads examined, and not one of them carrying the weight that some of them carry in other people. I am not telling you this to brag about my genetics — I did not choose them and neither did you. I am telling you because I spent years watching my family's health patterns and wondering what was moving through me that I could not see. Now I have looked at 59 places, and they are clear.
The second report was about pharmacogenomics — how my DNA affects the way medicines work in my body. My body processes certain things differently than the standard charts assume. Not badly. Just differently. I have shared this with my doctor. I am keeping an eye on it.
The DNA tells you what you were handed. It tells you which threads arrived with you before you had any say in the matter. What it cannot tell you is what you have done with them since. That is a different test entirely.
That test is still in the mail.
Sign up for All of Us at allofus.nih.gov. You give your data to science. Science gives you back a picture of yourself you cannot get anywhere else.
I found Fausto Polanco because I asked for a friend.
Not a store, not a market, not a thing to buy. I asked the universe for a friend in La Mision, and it sent me Carmen, who lives two doors down and has been there for twenty-three years. Carmen brought me to Fausto the way good friends bring you somewhere they love — quietly, without fanfare, as if sharing a secret they have been keeping for the right person.
Fausto was born in northern Baja before most of the roads were paved. Before the wave of American influence crossed the border and settled into everything. He grew up proud to be Mexican in a way that was specific and serious — the kind of pride that becomes a calling. He wanted to build something that reflected the beauty of what he came from. Something that said: this is where I am from, and it is extraordinary.
He started with one table and four chairs.
Then he started traveling. Into the villages of mainland Mexico, into the artisan communities, into the places where the hands that make things still know what they are making. He would arrive with a bottle of tequila, sit down with the locals, and stay long enough to understand what they were building and why. The people, he says, became his family. You can see it in what he carries back — not inventory, but love expressed as craft. Noble woods. Hand-tooled leather. Textiles woven by hands that learned from hands that learned from hands.
He calls what he has built Mestizo. A fusion of old Mexico and the modern world. A story, not a style.
I left his store with three things and the beginning of Signal Circle. I did not plan that. I just followed Carmen through the door.
That is the signal: the people who become your family will take you places Google will never find.
A woman in my mastermind — Katherine, based in the UK — has been quietly building something extraordinary. In thirteen months, she built a travel agency from nothing to six figures. It is growing fifteen percent every month. I watch her and I think: that is what it looks like when someone finds their thing and refuses to stop.
A few months ago, she extended an invitation I did not immediately understand. Join the agency. Not as a client. As an agent.
I said yes before I fully knew what I was saying yes to.
Here is what I know now. Travel agents have access to deals, rates, and last-minute inventory that the general public simply cannot see. Not slightly better — meaningfully better. The kind of pricing that changes the math on moving through the world. I travel between Long Beach, Roanoke, and La Mision. I am going to Basel in June. I drive past the port every day of my life and I have been following threads to places I did not expect.
I have never had a travel agent. Now I am one.
This is what a mastermind does, at its best. You sit in a room with women who are building things — and the things they are building become doors you can walk through. You pull one thread and it hands you something you were not looking for and could not have found alone.
I do not know yet everything this will become. That is the part I have stopped needing to know in advance.
If you move through the world the way I do — intentionally, often, toward things that matter — this may be a door worth considering. I will share more as I learn more.
(The thread continues.)
Stay curious. Stay in charge.
Holly
Curation in every breath, beat and blink.
Everything in Signal Edge reflects my own research, curiosity, and lived experience. I am not a licensed financial planner, certified tax advisor, registered investment advisor, or medical professional. Nothing here constitutes financial, investment, tax, legal, or medical advice. It is personal opinion, shared openly and honestly from one thinking person to another. Please consult qualified professionals before making decisions about your money, health, or property.
© Holly Culbreth / Signal Edge. All rights reserved.